Cholesterol Drugs, Prescriptions and Overseas Pharmacy Meds

Acitrom Sinthrom

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Nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the UK) which is a type of medicine called an oral anticoagulant. It is used to stop blood clots forming within the blood vessels. Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. The clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. Clotting factors are proteins that are produced by the liver. Vitamin K is essential for their production. The activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. Fibrin binds the platelets together forming a blood clot. This is the bodyЖs natural way of repairing itself. Sometimes however a blood clot can form abnormally within the blood vessels. This is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream where it becomes known as an embolus. The clot may eventually get lodged in a blood vessel thereby blocking the blood supply to a vital organ such as the heart brain or lungs. This is known as a thromboembolism.Some people have an increased tendency for blood clots to form within the blood vessels. This is usually due to a disturbance in the blood flow within the blood vessels. For example fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow giving a tendency for platelets to clump together and start off the clotting process. Slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). These clots can break off and travel to the lungs (pulmonary embolism). A type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. Heart valve disease can have the same effect particularly if artificial heart valves have been fitted. Clots in the heart can detach and travel to the brain causing a stroke. Acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. Acenocoumarol works by preventing the vitamin K dependent production of the clotting factors described above. Acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin K. Without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.Acenocoumarol takes about three days to produce its full anticoagulant effect because while it prevents the production of new clotting factors it takes about this long for clotting factors that have already been produced to be used up. For this reason when treating blood clots such as deep vein thrombosis (DVT) or pulmonary embolism a faster acting injectable anticoagulant such as a heparin is often used as well to begin with.The anticoagulant effect of acenocoumarol is measured in terms of the prothombin time which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. This time is expressed as the International Normalised Ratio (INR). Your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your INR fall into the range that has been shown to be effective at preventing blood clots in your particular condition.What is it used for?Treating and preventing blood clots in the blood vessels for example in the following cases:Preventing abnormal blood clots in conditions with increased risk eg rheumatic heart disease atrial fibrillation and after insertion of artificial (prosthetic) heart valves Treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) Treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism)

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Product Type: Prescription Drugs 1

Acitrom ( Sinthrom Generic Nicoumalone )

Acitrom (Sinthrom Generic Nicoumalone)

Sinthrom Generic Nicoumalone

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Cholesterol Drugs, Prescriptions and Overseas Pharmacy Meds: Atorvastatin (Lipitor) Atorvastatin belongs to the group of medicines called 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors. It works by blocking an enzyme that is needed by the body to make cholesterol thereby reducing the amount of cholesterol in the blood. Buy Atorvastatin (Lipitor) and other Cholesterol products online at Medstore. About Atorvastatin (Lipitor): Product Type: Cholesterol Brand name: Atorvastatin Generic name: Lipitor What is the most important information I should know about Atorvastatin? • Rare cases of muscle problems and liver problems have been associated with the use of Atorvastatin and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain tenderness or weakness especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes abdominal pain unexplained fatigue dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems. • Do not take Atorvastatin without first talking to your doctor if you have liver disease. • Alcohol and Atorvastatin can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined. • Do not take Atorvastatin if you are pregnant could become pregnant during treatment or if you are breast-feeding a baby. What is Atorvastatin? • Atorvastatin is an HMG CoA reductase inhibitor. Atorvastatin blocks the production of cholesterol (a type of fat) in the body. • Atorvastatin is used to reduce the amounts of LDL (bad) cholesterol total cholesterol triglycerides (another type of fat) and apolipoprotein B (a protein needed to make cholesterol) in your blood. Atorvastatin is also used to increase the level of HDL (good) cholesterol in your blood. These actions are important in reducing the risk of hardening of the arteries which can lead to heart attacks stroke and peripheral vascular disease. • Atorvastatin may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Atorvastatin? • Do not take Atorvastatin without first talking to your doctor if you have liver disease. • Before taking Atorvastatin tell your doctor if you drink alcoholic beverages have a chronic muscular disease require major surgery or have a blood disorder. • You may not be able to take Atorvastatin or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. • Atorvastatin is in the FDA pregnancy category X. This means that Atorvastatin is known to cause birth defects if it is taken during pregnancy. Do not take Atorvastatin if you are pregnant or could become pregnant during treatment. • It is not known whether Atorvastatin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. How should I take Atorvastatin? • Take Atorvastatin exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass of water. • Atorvastatin can be taken with or without food. • Atorvastatin is usually taken once a day. Try to take your dose at the same time each day. Follow your doctor's instructions. • Your doctor may want to monitor your liver function with blood tests before starting treatment with Atorvastatin at twelve weeks after both the start of your treatment and any increase in dose and periodically (every 6 months) thereafter. Depending on the results of these tests your doctor can determine how much monitoring you will require. • Grapefruit and grapefruit juice may interact with Atorvastatin. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Eat a low-fat low-cholesterol diet. To realize beneficial effects from Atorvastatin avoid fatty high-cholesterol foods. • It is important to take Atorvastatin regularly to get the most benefit. • Do not stop taking Atorvastatin without first talking to your doctor. Atorvastatin may need to be taken on a long-term basis for the treatment of high cholesterol. • Your doctor may want you to have blood tests or other medical evaluations during treatment with Atorvastatin to monitor progress and side effects. • Store Atorvastatin at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. However if it is almost time for the next dose skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention if an overdose is suspected. • The symptoms of an Atorvastatin overdose are not known. What should I avoid while taking Atorvastatin? • Alcohol and Atorvastatin can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined. • Grapefruit and grapefruit juice may interact with Atorvastatin. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. What are the possible side effects of Atorvastatin? • Rare cases of muscle problems and liver problems have been associated with the use of Atorvastatin and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain tenderness or weakness especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes abdominal pain unexplained fatigue dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems. • If you experience any of the following serious side effects stop taking Atorvastatin and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips tongue or face; or hives); decreased urine or rust-colored urine; or blurred vision. • Other less serious side effects may be more likely to occur. Continue to take Atorvastatin and talk to your doctor if you experience headache; upset stomach or flatulence; or a rash. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Atorvastatin? • Do not take Atorvastatin without first talking to your doctor if you are taking any of the following medicines: cyclosporine (Sandimmune Neoral); gemfibrozil (Lopid) clofibrate (Atromid-S) or fenofibrate (Tricor); niacin (Nicolar Nicobid Slo-Niacin others); erythromycin (E-Mycin E.E.S. Ery-Tab others) or clarithromycin (Biaxin); cholestyramine (Questran) or colestipol (Colestid); hormonal birth control (pills patches or implants); or an antifungal medication such as itraconazole (Sporanox) fluconazole (Diflucan) or ketoconazole (Nizoral). • You may not be able to take Atorvastatin or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. • Drugs other than those listed here may also interact with Atorvastatin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including vitamins minerals and herbal products. Generic Atorvastatin (Lipitor) Atropic Rovator Trovatin Cardyl Sotis Torvast Tozalip Xavator 10mg 120 tabs 10mg 180 tabs 20mg 60 tabs 10mg 60 tabs 40mg 240 tabs 10mg 240 tabs 20mg 90 tabs 20mg 120 tabs 40mg 30 tabs 10mg 480 tabs 40mg 120 tabs 20mg 240 tabs 40mg 60 tabs 20mg 30 tabs 40mg 90 tabs Lipitor Atorvastatin