Cholesterol Drugs, Prescriptions and Overseas Pharmacy Meds

Arava (Leflunomide)

Cholesterol Drugs, Prescriptions and Overseas Pharmacy Meds » Arthritis » Arava (Leflunomide)

Arava (Leflunomide) is a pyrimidine synthesis inhibitor used to treat rheumatoid arthritis. This medicine may be used to reduce the signs and symptoms of rheumatoid arthritis slow the development of damage to the joints and to improve physical function.

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About Arava (Leflunomide):

Product Type: Arthritis

Brand name: Arava Generic name: Leflunomide What is the most important information I should know about Arava? • Arava is in the FDA pregnancy category X. There is an increased risk of birth defects and death of the unborn baby while taking Arava. Do not take this medication if you are pregnant or could become pregnant during treatment. Notify your doctor immediately if you think you have become pregnant during treatment. Birth control must be used during treatment with Arava. Discuss with your doctor the procedure for removing Arava from the body following treatment before becoming pregnant. Without the proper drug elimination procedure it may take up to two years before Arava is at sufficiently low levels in the body so as to reduce the risk of harm to an unborn baby. It is not known whether Arava imposes an increased risk of fetal harm when taken by a man. Men wishing to father a child while taking Arava should discuss their options with their doctor. What is Arava? • Arava affects the immune system and decreases inflammation. • Arava is used to reduce the signs and symptoms of rheumatoid arthritis reduce damage to the joints caused by rheumatoid arthritis and to improve physical function in people with rheumatoid arthritis. • Arava may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Arava? • Before taking Arava tell your doctor if you have liver disease or a history of hepatitis; a history of significant alcohol use; kidney disease; an immune system disease; recently received a live vaccine; poor bone marrow function; or a current or chronic infection. • You may not be able to take Arava or you may require a dosage adjustment or special monitoring during your treatment if you have any of the conditions listed above. • Arava is in the FDA pregnancy category X. There is an increased risk of birth defects and death of the unborn baby while taking Arava. Do not take this medication if you are pregnant or could become pregnant during treatment. Notify your doctor immediately if you think you have become pregnant during treatment. Birth control must be used during treatment with Arava. Discuss with your doctor the procedure for removing Arava from the body following treatment before becoming pregnant. Without the proper drug elimination procedure it may take up to two years before Arava is at sufficiently low levels in the body so as to reduce the risk of harm to an unborn baby. It is not known whether Arava imposes an increased risk of fetal harm when taken by a man. Men wishing to father a child while taking Arava should discuss their options with their doctor. • It is not known whether Arava passes into breast milk. There is a potential for serious side effects in a nursing baby from Arava. Do not take Arava if you are breast-feeding a baby. How should I take Arava? • Take Arava exactly as directed by your doctor. If you do not understand these instructions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass of water. • Arava can be taken with or without food or milk. • It is important to take Arava regularly to get the most benefit. • Your doctor may want you to have blood tests or other medical evaluations while taking Arava to monitor side effects and progress. • Store Arava at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for your next dose skip the missed dose and only take your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor. What happens if I overdose? • Seek emergency medical attention if an overdose is suspected. • Symptoms of a Arava overdose may include diarrhea abdominal pain blood problems and liver problems. What should I avoid while taking Arava? • Discuss with your doctor the use of alcohol while taking Arava. Alcohol and Arava can both be damaging to the liver. • Arava can lower the activity of the immune system making you more susceptible to infection. Avoid contact with people who have colds the flu or other contagious illnesses. In addition do not receive vaccines that contain a live strain of the virus (e.g. live oral polio vaccine) and avoid contact with individuals who have recently been vaccinated with a live virus. What are the possible side effects of Arava? • If you experience any of the following serious side effects stop taking Arava and seek medical treatment or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips tongue or face; or hives); changes in liver function (may be detected by blood tests or cause symptoms such as yellowing of the skin or eyes; pale colored stools or dark colored urine; unusual fatigue; or abdominal pain); decreased bone marrow function or blood problems (may be detected by blood tests or cause symptoms such as extreme or unusual fatigue; easy bruising or bleeding; black bloody or tarry stools; fever or chills; or signs of infection such as fever; chills or sore throat); or skin rash; or sores in the mouth. • Other less serious side effects may be more likely to occur. Continue to take Arava and talk to your doctor if you experience headache; increased blood pressure; muscle aches; nausea; diarrhea; or hair loss. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Arava? • Before taking Arava tell your doctor if you are taking any of the following drugs: cholestyramine (Questran Prevalite LoCHOLEST); methotrexate (Rheumatrex); or rifampin (Rifadin Rimactane). • You may not be able to take Arava or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. • Drugs other than those listed here may also interact with Arava. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines including vitamins minerals and herbal products

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These may be early symptoms of muscle or liver problems. • Do not take Atorvastatin without first talking to your doctor if you have liver disease. • Alcohol and Atorvastatin can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined. • Do not take Atorvastatin if you are pregnant could become pregnant during treatment or if you are breast-feeding a baby. What is Atorvastatin? • Atorvastatin is an HMG CoA reductase inhibitor. Atorvastatin blocks the production of cholesterol (a type of fat) in the body. • Atorvastatin is used to reduce the amounts of LDL (bad) cholesterol total cholesterol triglycerides (another type of fat) and apolipoprotein B (a protein needed to make cholesterol) in your blood. Atorvastatin is also used to increase the level of HDL (good) cholesterol in your blood. 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Do not take Atorvastatin if you are pregnant or could become pregnant during treatment. • It is not known whether Atorvastatin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. How should I take Atorvastatin? • Take Atorvastatin exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass of water. • Atorvastatin can be taken with or without food. • Atorvastatin is usually taken once a day. Try to take your dose at the same time each day. Follow your doctor's instructions. • Your doctor may want to monitor your liver function with blood tests before starting treatment with Atorvastatin at twelve weeks after both the start of your treatment and any increase in dose and periodically (every 6 months) thereafter. 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What happens if I miss a dose? • Take the missed dose as soon as you remember. However if it is almost time for the next dose skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention if an overdose is suspected. • The symptoms of an Atorvastatin overdose are not known. What should I avoid while taking Atorvastatin? • Alcohol and Atorvastatin can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined. • Grapefruit and grapefruit juice may interact with Atorvastatin. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. What are the possible side effects of Atorvastatin? • Rare cases of muscle problems and liver problems have been associated with the use of Atorvastatin and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain tenderness or weakness especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes abdominal pain unexplained fatigue dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems. • If you experience any of the following serious side effects stop taking Atorvastatin and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips tongue or face; or hives); decreased urine or rust-colored urine; or blurred vision. • Other less serious side effects may be more likely to occur. 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